ncRNA name | FoxO1A siRNA |
ncRNA Category | siRNA |
Disease name | cataract |
Species | Homo sapiens |
Tissues/Cell_line | primary human lens epithelial cells (LECs) |
Methods | flow cytometry, qPCR, Western blot, siRNA transfection |
Expression pattern | associated |
Functional description | SiRNA inhibition of FoxO1A, FoxO3A, and FoxO4 not only led to loss of the anti-apoptotic effects of RES in stressed cells but actually exhibited a mild pro-apoptotic effect. |
PubMed ID | 21345980 |
Year | 2011 |
Title | Resveratrol prevention of oxidative stress damage to lens epithelial cell cultures is mediated by forkhead box O activity. |
Drug-related ncRNA | NO |
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